UMC Study on Diabetes

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Submitted by cwilson on Wed, 07/30/2008 - 22:58.

I found this article and wanted to share it.

Obesity and Diabetes; New obesity and diabetes findings from University of Mississippi Medical Center described
Anonymous. Diabetes Week. Atlanta: Aug 4, 2008. pg. 123

Abstract (Summary)
This study examined the prevalence of metabolic syndrome and assessed its cross-sectional relationship to CVD in the Jackson Heart Study (JHS) cohort. A total of 5,302 participants aged >= 21 years who were recruited at baseline during 2000-2004 were analyzed for this study. Adjusted odds ratios (ORs) were estimated in a logistic regression analysis for coronary heart disease (CHD) and cerebrovascular disease (CBD) in those with and without coexisting metabolic syndrome. Diabetic participants were excluded. Among those aged 35-84 years, metabolic syndrome prevalence was 43.3% in women and 32.7% in men. Elevated blood pressure (70.4%), abdominal obesity (64.6%), and low HDL cholesterol (37.2%) were highly prevalent among those with metabolic syndrome. Prevalence rates for CVD, CHD, and CBD were 12.8, 8.7, and 5.8%, respectively.

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Full Text (394 words)

2008 AUG 4 - ( NewsRx.com) -- "Health of African Americans is seriously threatened by unremitting epidemics of diabetes and cardiovascular disease (CVD) (see also Obesity and Diabetes). However, the role of metabolic syndrome in the African-American population has not been investigated widely," scientists in the United States report.

"This study examined the prevalence of metabolic syndrome and assessed its cross-sectional relationship to CVD in the Jackson Heart Study (JHS) cohort. A total of 5,302 participants aged >= 21 years who were recruited at baseline during 2000-2004 were analyzed for this study. Adjusted odds ratios (ORs) were estimated in a logistic regression analysis for coronary heart disease (CHD) and cerebrovascular disease (CBD) in those with and without coexisting metabolic syndrome. Diabetic participants were excluded. Among those aged 35-84 years, metabolic syndrome prevalence was 43.3% in women and 32.7% in men. Elevated blood pressure (70.4%), abdominal obesity (64.6%), and low HDL cholesterol (37.2%) were highly prevalent among those with metabolic syndrome. Prevalence rates for CVD, CHD, and CBD were 12.8, 8.7, and 5.8%, respectively. After adjustment for age and sex, metabolic syndrome was associated with increased age- and sex-adjusted ORs for CVD (OR 1.7 [95% CI 1.4-2.1]), CHD (1.7 [1.4-2.2]), and CBD (1.7 [1.3-2.3]) compared with those without CVD, CHD, or CBD. metabolic syndrome prevalence in the JHS is among the highest reported for population-based cohorts worldwide and is significantly associated with increased ORs for CVD, CHD, and CBD. Abdominal obesity, increased blood pressure, and low HDL cholesterol (without triglyceride elevation) are surprisingly prominent," wrote H. Taylor and colleagues, University of Mississippi Medical Center.

The researchers concluded: "A high prevalence of low HDL emerges as a leading contributor to metabolic syndrome among African Americans in this large African-American cohort."

Taylor and colleagues published their study in Diabetes Care (Distinct component profiles and high risk among African Americans with metabolic syndrome - The Jackson Heart Study. Diabetes Care, 2008;31(6):1248-1253).

For additional information, contact H. Taylor, University of Mississippi, Medical Center, Jackson State University, 2500 N State St., Jackson, MS 39216, USA.

The publisher's contact information for the journal Diabetes Care is: American Diabetes Association, 1701 N Beauregard St., Alexandria, VA 22311-1717, USA.

Keywords: United States, Jackson, Obesity, Obesity and Diabetes, University of Mississippi Medical Center.